Human Studies

CHRISTINA BURKE, M.A., is a senior research assistant in the Department of Psychiatry at the University of California, San Diego, and at the Veterans Medical Research Foundation, San Diego, California. Many people begin to drink alcohol during adolescence and young adulthood. Alcohol consumption during this developmental period may have profound effects on brain structure and function. Heavy drinking has been shown to affect the neuropsychological performance (e.g., memory functions) of young people and may impair the growth and integrity of certain brain structures. Furthermore, alcohol consumption during adolescence may alter measures of brain functioning, such as blood flow in certain brain regions and electrical brain activities. Not all adolescents and young adults are equally sensitive to the effects of alcohol consumption, however. Moderating factors—such as family history of alcohol and other drug use disorders, gender, age at onset of drinking, drinking patterns, use of other drugs, and co-occurring psychiatric disorders—may influence the extent to which alcohol consumption interferes with an adolescent’s normal brain development and functioning.